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The G Protein - Coupled Receptors Handbook

A comprehensive survey of the many recent advances in the field of G protein-coupled receptors (GPCR). The authors describe the current knowledge of GPCR receptor structure and function, the different mechanisms involved in the regulation of GPCR function, and the role of pharmacological chaperones in GPCR folding and maturation. They also present new findings about how GPCR dimerization/oligomerization modifies the properties of individual receptors and show how recent developments are leading to significant advances in drug discovery, such as the detection of ligands for orphan GPCRs. Also discussed are the most recent developments that could lead to new drug discoveries: the role of GPCRs in mediating pain, the development of receptor-type selective drugs based on the structural plasticity of receptor activation, and the identification of natural ligands of orphan GPCRs (deorphanization) as possible drug targets.

Ketersediaan
221010567572.6 DEV t c.1Perpustakaan Pusat ITERA (Rak Klas 500)Tersedia
Informasi Detail
Judul Seri
-
No. Panggil
572.6 DEV t
Penerbit
New Jersey : Humana Press.,
Deskripsi Fisik
xv+412hlm.;ilust
Bahasa
Inggris
ISBN/ISSN
978-158829-635-3
Klasifikasi
572.6
Tipe Isi
-
Tipe Media
-
Tipe Pembawa
-
Edisi
First Edition
Subjek
Biology
Protein
Info Detail Spesifik
-
Pernyataan Tanggungjawab
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Tidak tersedia versi lain

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